A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...
Researchers have identified a new molecular target for treating pancreatic cancer. Scientists focused on transcription-replication conflicts (TRCs), which occur when the mechanisms responsible for ...
DNA polymerase epsilon catalytic subunit A (POLE) gene plays a crucial role in DNA repair and chromosomal replication. Mutations in the POLE gene have been linked to cancer, particularly colorectal ...
When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells. If they stop functioning or there's not ...
Researchers uncover how a key human immune protein curbs H5N1 avian flu, but the virus is evolving—could we be on the brink of a new zoonotic threat? Research Letter: Replication Restriction of ...
Melanoma kills roughly 8,000 Americans each year, and a stubborn share of those deaths trace back to the same problem: tumors ...
Respiratory Syncytial Virus (RSV) is a common childhood disease. Most people catch and recover from it by the age of three.