A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides ...
Georgia Tech researchers demonstrated the mechanics behind neural tube closure, which can lead to severe or fatal birth defects if unsuccessful.
Scientists at St. Jude Children’s Research Hospital imaged cellular projections called cytonemes that transfer signals across long distances during development St. Jude Children’s Research Hospital ...
A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...
Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...
In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close properly. Georgia Tech physicists are now helping explain why this happens, having ...
Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning. St. Jude Children's Research Hospital ...
St. Jude Children's Research Hospital scientists found that cytonemes (thin, long, hair-like projections on cells) are important during neural development. Cytonemes connect cells communicating across ...