A streamlined gene editing platform enables tissue-wide CRISPR screening in human organoids, identifying genes that regulate ...

A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...

The US Food and Drug Administration (FDA) mandated folic acid fortification of all enriched cereal grains in 1996, and this regulation resulted in a reduction of neural tube defect (NTD)–affected ...

Anencephaly occurs when an infant is born without parts of their brain and skull. It is a severe congenital anomaly, which means that a baby develops anencephaly in the womb. Anencephaly is a ...

Analysis of U.S. survey data showed that two-thirds of reproductive age women had one or more modifiable risk factors for birth defects. Common risk factors included obesity, folate concentrations ...

If you've been to a museum about the history of medicine or surgery, you've probably seen loads of preserved human remains that have been used as teaching aids or in scientific research. Access to ...

A task force set up by the National Academy of Medical Sciences says adding folic acid and vitamin B12 to tea could help prevent thousands of neural tube defects serious birth defects affecting the br ...

Please provide your email address to receive an email when new articles are posted on . One study found a reduced risk for neural tube defects when folic acid was used before and during pregnancy. The ...

Study coordinators who want to add a study should Submit a Clinical Trial. For more information or to remove a study, please email pa-webteam@bcm.edu. MyChart is a ...