When measuring with light, the lateral extent of the structures that can be resolved by an optical imaging system is fundamentally diffraction limited. Overcoming this limitation is a topic of great ...

Due to the inherent anisotropy of the optical PSF, the HR lateral images naturally serve as the rational gold standard for enhancing the axial resolution of the raw data. The unpaired lateral and ...

The 3D micro-device consists of a modified coverslip and a micro-sphere fabricated by advanced MPL. It can enhance the lateral resolution beyond what is achievable with conventional optics. Today, ...

Limited by the laws of physics, scientific discoveries and the advance of knowledge can be bound up in a series of slow proceedings. In microscopy, up until the early 21 st century, the diffraction ...