Empagliflozin reduced proinflammatory cytokines and oxidative stress markers in INOCA patients with CMD, improving vascular health. Treatment led to favorable shifts in endothelial extracellular ...

A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...

Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide. A growing body of evidence identifies endothelial dysfunction as ...

Sepsis, a life-threatening systemic inflammatory response triggered by infection, has long challenged clinicians with its persistently high mortality (up to 40-50% in septic shock). At the heart of ...

The glycocalyx emerges as an active endothelial system whose structure, metabolism, and shear-dependent regulation integrate mechanical forces with vascular signaling. Disruption of this system ...