Researchers have clarified the roles of matrix stiffness and mechanotransduction as well as the signaling pathways in the transformation of cardiac fibroblasts into contractile cardiomyocytes and show ...
BACKGROUND: Direct reprogramming of cardiac fibroblasts (CFs) into induced cardiomyocytes (iCMs) holds promise as a therapeutic strategy for heart regeneration. After myocardial infarction (MI), ...
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