Purinergic signaling, mediated by extracellular nucleotides such as ATP and UTP, has been increasingly studied for its role in regulating cellular communication. A new review by researchers in ...

A previous trial involving patients with metastatic prostate cancer that was resistant to androgen pathway modulation (formerly referred to as castration-resistant) showed that adding talazoparib ...

Our body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, ...

For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are ...

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology. Published in the renowned journal ...

Immunotherapy has transformed cancer care, offering a way to harness the body’s own immune system to fight tumors. But even with these advances, many patients still don’t respond. One major barrier to ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

Stopping cancer from coming back is the goal of new research from MUSC Hollings Cancer Center, where scientists are targeting cells that fuel the return of an aggressive pediatric brain tumor.

A new study leverages a modified pyrvinium hybrid to block GLI and WNT pathways, halting pediatric medulloblastoma relapse.

Social factors presented in the outer circle and physiological factors in the inner circle are common sources of chronic stress. Social factors include poor pre- or post-delivery care, emotional ...